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. 2008 Mar;14(3):502-4.
doi: 10.3201/eid1403.070843.

Sylvatic dengue virus type 2 activity in humans, Nigeria, 1966

Nikos Vasilakis  1 , Robert B Tesh, Scott C Weaver
Affiliations

Sylvatic dengue virus type 2 activity in humans, Nigeria, 1966

Nikos Vasilakis et al. Emerg Infect Dis. 2008 Mar.

Abstract

Using phylogenetic analysis of complete virus genomes from human isolates obtained in Nigeria in 1966, we identified sylvatic dengue virus (DENV) strains from 3 febrile patients. This finding extends current understanding of the role of sylvatic DENV in febrile disease and documents another focus of sylvatic DENV transmission in West Africa.

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Figures

Figure
Figure
Phylogenetic relationships of 3 complete coding regions of Nigerian dengue virus type 2 (DENV-2) isolates obtained from febrile patients in Ibadan, Nigeria, during the 1966 rainy season. A total of 15 sylvatic DENV-2 genomes (shaded) were compared with human isolates of DENV-2 and representatives of DENV-1, DENV-3, and DENV-4. Phylogeny was inferred by using Bayesian analysis, and all horizontal branches are scaled according to the number of substitutions per site. Bootstrap values are shown for key nodes.
See this image and copyright information in PMC

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