Microvascular function and ageing L-arginine, tetrahydrobiopterin and the search for the fountain of vascular youth
- PMID: 18325977
- PMCID: PMC2465197
- DOI: 10.1113/jphysiol.2008.151381
Microvascular function and ageing L-arginine, tetrahydrobiopterin and the search for the fountain of vascular youth
Comment on
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Ageing diminishes endothelium-dependent vasodilatation and tetrahydrobiopterin content in rat skeletal muscle arterioles.J Physiol. 2008 Feb 15;586(4):1161-8. doi: 10.1113/jphysiol.2007.147686. Epub 2007 Dec 6. J Physiol. 2008. PMID: 18063659 Free PMC article.
References
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- Holowatz LA, Thompson CS, Kenney WL. Acute ascorbate supplementation alone or combined with arginase inhibition augments reflex cutaneous vasodilation in aged human skin. Am J Physiol Heart Circ Physiol. 2006;291:H2965–H2970. - PubMed
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- Schmidt TS, Alp NJ. Mechanisms for the role of tetrahydrobiopterin in endothelial function and vascular disease. Clin Sci (Lond) 2007;113:47–63. - PubMed
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