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Review
. 2008 Mar-Apr;5(2):234-42.
doi: 10.1021/mp7001544. Epub 2008 Mar 11.

In vivo and in vitro production options for fungal secondary metabolites

Patrick Schneider  1 , Mathias Misiek, Dirk Hoffmeister
Affiliations
Review

In vivo and in vitro production options for fungal secondary metabolites

Patrick Schneider et al. Mol Pharm. 2008 Mar-Apr.

Abstract

Microbial natural products, among them a vast diversity of fungal origin, represent a major source for new drug candidates. Focusing on fungal metabolites, our review covers recent advances in the field of biotransformation, heterologous expression, in vivo production approaches, genomics, and the metabolism of unexplored fungal groups as options to generate and identify new compounds or optimize known ones.

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