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. 2008 Apr;8(4):1202-6.
doi: 10.1021/nl0802032. Epub 2008 Mar 11.

Isolation of discrete nanoparticle-DNA conjugates for plasmonic applications

Shelley A Claridge  1 , Huiyang W Liang, S Roger Basu, Jean M J Fréchet, A Paul Alivisatos
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Free article

Isolation of discrete nanoparticle-DNA conjugates for plasmonic applications

Shelley A Claridge et al. Nano Lett. 2008 Apr.
Free article

Abstract

Discrete DNA-gold nanoparticle conjugates with DNA lengths as short as 15 bases for both 5 and 20 nm gold particles have been purified by anion-exchange HPLC. Conjugates comprising short DNA (<40 bases) and large gold particles (> or =20 nm) are difficult to purify by other means and are potential substrates for plasmon coupling experiments. Conjugate purity is demonstrated by hybridizing complementary conjugates to form discrete structures, which are visualized by TEM.

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