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Review
. 2008 May;68(3):538-46.
doi: 10.1111/j.1365-2958.2008.06181.x. Epub 2008 Mar 4.

Modus operandi of the bacterial RNA polymerase containing the sigma54 promoter-specificity factor

Sivaramesh Wigneshweraraj  1 , Daniel Bose, Patricia C Burrows, Nicolas Joly, Jörg Schumacher, Mathieu Rappas, Tillmann Pape, Xiaodong Zhang, Peter Stockley, Konstantin Severinov, Martin Buck
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Free article
Review

Modus operandi of the bacterial RNA polymerase containing the sigma54 promoter-specificity factor

Sivaramesh Wigneshweraraj et al. Mol Microbiol. 2008 May.
Free article

Abstract

Bacterial sigma (sigma) factors confer gene specificity upon the RNA polymerase, the central enzyme that catalyses gene transcription. The binding of the alternative sigma factor sigma(54) confers upon the RNA polymerase special functional and regulatory properties, making it suited for control of several major adaptive responses. Here, we summarize our current understanding of the interactions the sigma(54) factor makes with the bacterial transcription machinery.

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