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Comment
. 2008 Mar;14(3):315-6.
doi: 10.1016/j.devcel.2008.02.010.

Yorkie and Scalloped: partners in growth activation

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Yorkie and Scalloped: partners in growth activation

Jennifer L Bandura et al. Dev Cell. 2008 Mar.
Free article

Abstract

The Hippo (Hpo) signaling pathway limits organ growth in organisms from Drosophila to mammals by suppressing the activity of the transcriptional coactivator Yorkie (Yki)/YAP. The TEAD/TEF factor Scalloped (Sd) has been identified as the first known transcription factor to partner with Yki as a downstream target of Hpo signaling.

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