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Comment
. 2008 Mar;14(3):320-2.
doi: 10.1016/j.devcel.2008.02.008.

sSgo1, a guardian of centriole cohesion

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sSgo1, a guardian of centriole cohesion

William Y Tsang et al. Dev Cell. 2008 Mar.
Free article

Abstract

Sgo1 plays a key role in protecting sister chromatid cohesion during mitosis. In this issue of Developmental Cell, Wang et al. describe a shorter splice variant of Sgo1 (sSgo1) that functions specifically in centriole cohesion. sSgo1 may be the "glue" that holds paired centrioles together in an engaged state before their disengagement in late mitosis.

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