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Review
. 2008;75(2):121-33.
doi: 10.1159/000113629. Epub 2008 Mar 6.

Pathophysiology of the pleura

Michael A Jantz  1 , Veena B Antony
Affiliations
Review

Pathophysiology of the pleura

Michael A Jantz et al. Respiration. 2008.

Abstract

The pleural mesothelial cell is an essential cell in maintaining the normal homeostasis of the pleural space and it is also a central component of the pathophysiologic processes affecting the pleural space. In this review, we will review the defense mechanisms of the pleural mesothelium and changes in pleural physiology as a result of inflammatory, infectious, and malignant conditions with a focus on cytokine and chemokine networks. We will also review the processes involved in the pathogenesis of pleural fibrosis.

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