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Comparative Study
. 2008 May 30;159(1-2):25-30.
doi: 10.1016/j.psychres.2007.05.010. Epub 2008 Mar 11.

Implications of the DSM's emphasis on sadness and anhedonia in major depressive disorder

Julia D Buckner  1 , Thomas E Joiner Jr, Jeremy W Pettit, Peter M Lewinsohn, Norman B Schmidt
Affiliations
Comparative Study

Implications of the DSM's emphasis on sadness and anhedonia in major depressive disorder

Julia D Buckner et al. Psychiatry Res. .

Abstract

At least five symptoms must occur for a DSM diagnosis of major depressive disorder (MDD), one of which must be sadness or anhedonia. The present study is the first known investigation of the implications of the presence or absence of these prioritized symptoms on symptom expression and clinical characteristics among 564 young adults with MDD. Differences in symptom expression and clinical characteristics occurred among MDD participants with sadness relative to those without sadness as well as among MDD participants with anhedonia relative to those without anhedonia. Differential symptom expression could have important implications for the etiology, prevention, and treatment of MDD.

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