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Review
. 2008;15(3):238-43.
doi: 10.2174/092986608783744252.

Host defense peptides and the new line of defence against multiresistant infections

Tobias Hirsch  1 , Frank Jacobsen, Hans-Ulrich Steinau, Lars Steinstraesser
Affiliations
Review

Host defense peptides and the new line of defence against multiresistant infections

Tobias Hirsch et al. Protein Pept Lett. 2008.

Abstract

Increasing antibiotic resistance has led to an urgent need for new therapeutic approaches. Host defense peptides are known to be antimicrobial and have revealed broad immunomodulatory functions for both innate and adaptive immunity. This review will focus on the role of host defense peptides in infection and immune response and discuss its potential and limitations as a future therapeutical agent.

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