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Review
. 2008 Mar 15;336(7644):590-3.
doi: 10.1136/bmj.39506.601053.BE.

Genetic tests for common diseases: new insights, old concerns

David Melzer  1 , Stuart Hogarth, Katherine Liddell, Tom Ling, Simon Sanderson, Ron L Zimmern
Affiliations
Review

Genetic tests for common diseases: new insights, old concerns

David Melzer et al. BMJ. .

Abstract

The clinical utility of newly identified genetic variants associated with common diseases needs evaluation

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Conflict of interest statement

Competing interests: DM holds an unrestricted research grant from the BUPA Foundation.

Comment in

References

    1. Melzer D, Hurst AJ, Frayling T. Genetic variation and human aging: progress and prospects. J Gerontol A Biol Sci Med Sci 2007;62:301-7. - PubMed
    1. International HapMap Consortium. A second generation human haplotype map of over 3.1 million SNPs. Nature 2007;449:851-61. - PMC - PubMed
    1. Morgan TM, Krumholz HM, Lifton RP, Spertus JA. Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study. JAMA 2007;297:1551-61. - PubMed
    1. Thakkinstian A, Han P, McEvoy M, Smith W, Hoh J, Magnusson K, et al. Systematic review and meta-analysis of the association between complementary factor H Y402H polymorphisms and age-related macular degeneration. Hum Mol Genet 2006;15:2784-90. - PubMed
    1. Baurecht H, Irvine AD, Novak N, Illig T, Buhler B, Ring J, et al. Toward a major risk factor for atopic eczema: meta-analysis of filaggrin polymorphism data. J Allerg Clin Immunol 2007;120:1406-12. - PubMed

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