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Review
. 2008 Mar;28(3):297-9.
doi: 10.1016/j.immuni.2008.02.011.

Thymus lineage commitment: a single switch

Stephen M Hedrick  1
Affiliations
Free article
Review

Thymus lineage commitment: a single switch

Stephen M Hedrick. Immunity. 2008 Mar.
Free article

Abstract

In this issue of Immunity, He et al. (2008) establish the logic and circuitry that determine CD4-CD8 lineage specification. It all comes down to an eighty base pair silencer switch.

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