Living in context with the survival factor BAFF
- PMID: 18342003
- DOI: 10.1016/j.immuni.2008.02.010
Living in context with the survival factor BAFF
Abstract
In this issue, Gardham et al. (2008) show that BAFF, a tumor necrosis factor (TNF) family member, promotes B cell survival by hindering interactions between TNF-receptor-associated factors, blocking their negative regulation of nonclassical NF-kappaB activity.
Comment on
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TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor.Immunity. 2008 Mar;28(3):391-401. doi: 10.1016/j.immuni.2008.01.009. Epub 2008 Feb 28. Immunity. 2008. PMID: 18313334
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