Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Mar 14;29(5):539-40.
doi: 10.1016/j.molcel.2008.02.007.

Tat-SIRT1 tango

Dalibor Blazek  1 , B Matija Peterlin
Affiliations
Free article

Tat-SIRT1 tango

Dalibor Blazek et al. Mol Cell. .
Free article

Abstract

In a recent issue of Cell Host & Microbe, Kwon et al. (2008) report that the human immunodeficiency virus (HIV) transactivator Tat inhibits the SIRT1 deacetylase, resulting in increased acetylation of the NF-kappaB p65 subunit and subsequently in T cell hyperactivation.

PubMed Disclaimer

LinkOut - more resources