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Review
. 2008 Apr;1783(4):530-4.
doi: 10.1016/j.bbamcr.2008.02.009. Epub 2008 Feb 23.

Disulfide bond isomerization in prokaryotes

Stefan Gleiter  1 , James C A Bardwell
Affiliations
Review

Disulfide bond isomerization in prokaryotes

Stefan Gleiter et al. Biochim Biophys Acta. 2008 Apr.

Abstract

Proteins with multiple cysteine residues often require disulfide isomerization reactions before they attain their correct conformation. In prokaryotes this reaction is catalyzed mainly by DsbC, a protein that shares many similarities in structure and mechanism to the eukaryotic protein disulfide isomerase. This review discusses the current knowledge about disulfide isomerization in prokaryotes.

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