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. 2008;16(3):79-87.
doi: 10.1007/BF03086123.

Guidelines for heart transplantation

N de Jonge  1 , J H Kirkels, C Klöpping, J R Lahpor, K Caliskan, A P W M Maat, J Brügemann, M E Erasmus, R J M Klautz, H F Verwey, A Oomen, C H Peels, A E J Golüke, D Nicastia, M A C Koole, A H M M Balk
Affiliations

Guidelines for heart transplantation

N de Jonge et al. Neth Heart J. 2008.

Abstract

Based on the changes in the field of heart transplantation and the treatment and prognosis of patients with heart failure, these updated guidelines were composed by a committee under the supervision of both the Netherlands Society of Cardiology and the Netherlands Association for Cardiothoracic surgery (NVVC and NVT).THE INDICATION FOR HEART TRANSPLANTATION IS DEFINED AS: 'End-stage heart disease not remediable by more conservative measures'.CONTRAINDICATIONS ARE: irreversible pulmonary hypertension/elevated pulmonary vascular resistance; active systemic infection; active malignancy or history of malignancy with probability of recurrence; inability to comply with complex medical regimen; severe peripheral or cerebrovascular disease and irreversible dysfunction of another organ, including diseases that may limit prognosis after heart transplantation.Considering the difficulties in defining end-stage heart failure, estimating prognosis in the individual patient and the continuing evolution of available therapies, the present criteria are broadly defined. The final acceptance is done by the transplant team which has extensive knowledge of the treatment of patients with advanced heart failure on the one hand and thorough experience with heart transplantation and mechanical circulatory support on the other hand. (Neth Heart J 2008;16:79-87.).

Keywords: guidelines; heart failure; heart transplantation.

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Figures

Figure 1A
Figure 1A
The number of heart transplantations in the Netherlands per year.
Figure 1B
Figure 1B
The number of heart transplantations worldwide, according to the ISHLT.
Figure 2
Figure 2
Predictors of in-hospital mortality according to the Acute Decompensated Heart Failure National Registry (ADHERE). BUN=blood urea nitrogen.
See this image and copyright information in PMC

References

    1. Taylor DO, Edwards LB, Boucek MM, Trulock EP, Waltz DA, Keck BM, et al. Registry of the International Society for Heart and Lung Transplantation: Twenty-third official adult heart transplantation report-2006. JHLTX 2006;25:869-79. - PubMed
    1. Balk AHHM, Maat APWM, Weimar W, de Jonge N, et al. Heart transplantation: guidelines for the referring cardiologist. Cardiologie 1998;5:702-15.
    1. Coppen R, Marquet RL, Friele RD. Het donorpotentieel. Een vergelijking van het donorpotentieel in Nederland en 9 andere West Europese landen. Nivel 2003.
    1. Kirkels JH, de Jonge N, Klöpping C, Lahpor JR, van Herwerden LA, Balk AHMM, et al. Heart transplantation in the Netherlands: quo vadis? Neth Heart J 2006;14:425-30. - PMC - PubMed
    1. Redfield MM. Heart failure-an epidemic of uncertain proportions. N Engl J Med 2002;347:1442-4. - PubMed

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