Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 Mar 22;336(7645):658-62.
doi: 10.1136/bmj.39493.511759.BE.

Diagnosis and management of motor neurone disease

Christopher J McDermott  1 , Pamela J Shaw
Affiliations
Review

Diagnosis and management of motor neurone disease

Christopher J McDermott et al. BMJ. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

None
Fig 1 Lower motor neurone loss leads to muscle wasting, particularly of first dorsal interossei (top), tibialis anterior (middle), and tongue (bottom)
None
Fig 2 Machine and masks for non-invasive ventilation
See this image and copyright information in PMC

References

    1. Scottish Motor Neuron Disease Register: a prospective study of adult onset motor neuron disease in Scotland. Methodology, demography and clinical features of incident cases in 1989. J Neurol Neurosurg Psychiatry 1992;55:536-41. - PMC - PubMed
    1. O’Toole O, Traynor BJ, Brennan P, Sheehan C, Frost E, Corr B, et al. Epidemiology and clinical features of amyotrophic lateral sclerosis in Ireland between 1995 and 2004. J Neurol Neurosurg Psychiatry 2008;79:30-2. - PubMed
    1. Worms PM. The epidemiology of motor neuron diseases: a review of recent studies. J Neurol Sci 2001;191:3-9. - PubMed
    1. Borasio GD, Sloan R, Pongratz DE. Breaking the news in amyotrophic lateral sclerosis. J Neurol Sci 1998;160(suppl 1):S127-33. - PubMed
    1. Lacomblez L, Bensimon G, Leigh PN, Guillet P, Meininger V. Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II. Lancet 1996;347:1425-31. - PubMed

MeSH terms