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. 2008 May;45(5):605-12.
doi: 10.1016/j.fgb.2008.02.002. Epub 2008 Feb 21.

New Paracoccidioides brasiliensis isolate reveals unexpected genomic variability in this human pathogen

Lilia L Carrero  1 , Gustavo Niño-Vega, Marcus M Teixeira, Maria Jose A Carvalho, Célia M A Soares, Maristela Pereira, Rosália S A Jesuino, Juan G McEwen, Leonel Mendoza, John W Taylor, Maria Sueli Felipe, Gioconda San-Blas
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New Paracoccidioides brasiliensis isolate reveals unexpected genomic variability in this human pathogen

Lilia L Carrero et al. Fungal Genet Biol. 2008 May.

Abstract

By means of genealogical concordance phylogenetic species recognition (GCPSR), we have investigated coding and non-coding regions from various genes and the ITS sequences of 7 new and 14 known isolates of Paracoccidioides brasiliensis. Such isolates grouped within the three phylogenetic groups recently reported in the genus Paracoccidioides, with one single exception, i.e., Pb01, a strain that has been the subject of intense molecular studies for many years. This isolate clearly separates from all other Paracoccidioides isolates in phylogenetic analyses and greatly increases the genomic variation known in this genus.

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