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Case Reports
. 2008 May;46(5):1878-80.
doi: 10.1128/JCM.00047-08. Epub 2008 Mar 26.

Identification of the first VIM metallo-beta-lactamase-producing multiresistant Aeromonas hydrophila strain

Balázs Libisch  1 , Christian G Giske, Bogáta Kovács, Tamás G Tóth, Miklós Füzi
Affiliations
Case Reports

Identification of the first VIM metallo-beta-lactamase-producing multiresistant Aeromonas hydrophila strain

Balázs Libisch et al. J Clin Microbiol. 2008 May.

Abstract

A VIM metallo-beta-lactamase-producing Aeromonas hydrophila strain carrying an integron-borne bla(VIM-4) gene was isolated from a cirrhotic patient's fecal sample in a Budapest hospital. The variable region of this integron is identical with that of a previously characterized integron from Pseudomonas aeruginosa clinical isolates in Pécs in southern Hungary.

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Figures

FIG. 1.
FIG. 1.
Etest MBL strip for the A. hydrophila isolate MB443. IP stands for imipenem concentrations (4 to 256 μg/ml) and IPI for imipenem (1 to 64 μg/ml) plus a constant level of EDTA. IP and IPI MICs should be read where the respective inhibition ellipses intersect the strip (AB Biodisk, Solna, Sweden).
FIG. 2.
FIG. 2.
Inhibitory zones for the A. hydrophila isolate MB443 around β-lactam disks with or without 750 μg EDTA. FOX, cefoxitin; CTX, cefotaxime; TZP, piperacillin-tazobactam.
FIG. 3.
FIG. 3.
The variable region of the integron of the VIM-4-producing A. hydrophila isolate MB443 characterized in this study. The empty ellipse represents the attI1 site, and black circles represent the 59-base elements. The asterisk indicates a blaVIM-4 cassette with the 170-bp duplication. 5′-CS and 3′-CS, 5′ and 3′ conserved sequences, respectively.
See this image and copyright information in PMC

References

    1. Abbott, S. L. 2003. Aeromonas, p. 701-705. In P. R. Murray, E. J. Baron, M. A. Pfaller, J. H. Jorgensen, and R. H. Yolken (ed.), Manual of clinical microbiology, 8th ed. ASM Press, Washington, DC.
    1. Adams, M. R., and M. O. Moss. 2000. Bacterial agents of foodborne illness. Aeromonas hydrophila, p. 184-186. In M. R. Adams and M. O. Moss (ed.), Food microbiology, 2nd ed. Royal Society of Chemistry, Cambridge, United Kingdom.
    1. Andrade, S. S., R. C. Picão, E. H. Campana, A. G. Nicoletti, A. C. Pignatari, and A. C. Gales. 2007. Influence of disk preparation on detection of metallo-β-lactamase-producing isolates by the combined disk assay. J. Clin. Microbiol. 452058-2060. - PMC - PubMed
    1. Barlow, R. S., J. M. Pemberton, P. M. Desmarchelier, and K. S. Gobius. 2004. Isolation and characterization of integron-containing bacteria without antibiotic selection. Antimicrob. Agents Chemother. 48838-842. - PMC - PubMed
    1. Chang, Y. C., D. Y. Shih, J. Y. Wang, and S. S. Yang. 2007. Molecular characterization of class 1 integrons and antimicrobial resistance in Aeromonas strains from foodborne outbreak-suspect samples and environmental sources in Taiwan. Diagn. Microbiol. Infect. Dis. 59191-197. - PubMed

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