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Clinical Trial
. 1991 Nov;30(11):806-9.
doi: 10.1111/j.1365-4362.1991.tb04793.x.

Ketoconazole 2% emulsion in the treatment of seborrheic dermatitis

G E Piérard  1 , C Piérard-Franchimont, J Van Cutsem, A Rurangirwa, M L Hoppenbrouwers, P Schrooten
Affiliations
Clinical Trial

Ketoconazole 2% emulsion in the treatment of seborrheic dermatitis

G E Piérard et al. Int J Dermatol. 1991 Nov.

Abstract

Fifty patients (42 men, 8 women) with seborrheic dermatitis were included in the trial. Ketoconazole 2% emulsion or the same emulsion without active drug was applied b.i.d. for 4 weeks. Two patients dropped out in the ketoconazole group and nine in the placebo group. Pityrosporum ovale was cultured from all patients at the start and from six out of 23 in the ketoconazole group versus nine out of 16 in the placebo group at week 4. The overall assessment showed a significantly better response to treatment for the ketoconazole emulsion (72%) than for the placebo (32%).

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