Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 Mar:18 Suppl 1:2-7.
doi: 10.1007/s10286-007-1004-0. Epub 2008 Mar 27.

The pathophysiology and diagnosis of orthostatic hypotension

David Robertson  1
Affiliations
Review

The pathophysiology and diagnosis of orthostatic hypotension

David Robertson. Clin Auton Res. 2008 Mar.

Abstract

Orthostatic Hypotension (OH) is a common manifestation of blood pressure dysregulation. OH takes a heavy toll on quality of life. It has many potential etiologies, and many effects of aging can increase susceptibility to OH. Neurological disorders are especially likely to cause severe OH. In this brief review, the pathogenesis of OH is considered, particularly in terms of autonomic neuropathy, multiple system atrophy (MSA), pure autonomic failure, baroreflex failure, and dopamine beta hydroxylase deficiency. While OH is difficult to treat, its control greatly enhances the quality of life.

PubMed Disclaimer

References

    1. Hypertension. 1985 Mar-Apr;7(2):196-203 - PubMed
    1. Clin Sci (Lond). 2007 Nov;113(10):401-7 - PubMed
    1. J Neurol Sci. 2002 Aug 15;200(1-2):1-10 - PubMed
    1. J Am Geriatr Soc. 1988 Jan;36(1):84 - PubMed
    1. Neurology. 2001 Apr 10;56(7):980-1 - PubMed

Publication types

MeSH terms