Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2008;40(2):471-5.
doi: 10.1007/s11255-008-9356-5.

Spectrum of renal involvement in paroxysmal nocturnal hemoglobinuria: report of three cases and a brief review of the literature

R K Nair  1 , Ambar Khaira, Alok Sharma, Sandeep Mahajan, Amit K Dinda
Affiliations
Case Reports

Spectrum of renal involvement in paroxysmal nocturnal hemoglobinuria: report of three cases and a brief review of the literature

R K Nair et al. Int Urol Nephrol. 2008.

Abstract

Renal involvement in paroxysmal nocturnal hemoglobinuria (PNH) is usually clinically not apparent but, in cases with clinical involvement, varies from reversible acute dysfunction to chronic irreversible damage. We report two cases of acute kidney injury and one case of chronic kidney disease due to PNH. In all three cases a diagnosis of PNH was made after detection of renal dysfunction. The renal involvement was documented on both histology and on imaging studies. Finally, we briefly review the main literature data on renal involvement in PNH.

PubMed Disclaimer

References

    1. Am J Physiol. 1989 Mar;256(3 Pt 2):F446-55 - PubMed
    1. Nephrol Dial Transplant. 1988;3(5):708-9 - PubMed
    1. Postgrad Med J. 1981 Nov;57(673):736-8 - PubMed
    1. Clin Nephrol. 2001 Aug;56(2):172-4 - PubMed
    1. Blood. 1981 Jan;57(1):83-9 - PubMed

Publication types

LinkOut - more resources