Is Ewing's sarcoma a stem cell tumor?
- PMID: 18371327
- DOI: 10.1016/j.stem.2007.05.011
Is Ewing's sarcoma a stem cell tumor?
Abstract
Solving the histogenesis of Ewing's sarcoma has defied investigators despite progress in understanding its molecular pathogenesis. In a recent issue of Cancer Cell, Tirode et al. (2007) present evidence supporting the hypothesis that this rare cancer arises from a primitive mesenchymal precursor.
Similar articles
-
Esophageal extraskeletal neoplasm Ewing's sarcoma: Case report.Int J Surg Case Rep. 2022 Aug;97:107399. doi: 10.1016/j.ijscr.2022.107399. Epub 2022 Jul 9. Int J Surg Case Rep. 2022. PMID: 35926382 Free PMC article.
-
What's new in Ewing's tumor?Pathol Res Pract. 1993 Jun;189(5):616-20. doi: 10.1016/S0344-0338(11)80384-5. Pathol Res Pract. 1993. PMID: 8378185 Review.
-
[Pathology of Ewing sarcoma].Pathologe. 1996 Jan;17(1):6-17. doi: 10.1007/s002920050129. Pathologe. 1996. PMID: 8685098 Review. German.
-
Neurogenic potential of Ewing's sarcoma cells.Virchows Arch. 1997 Jan;430(1):41-6. doi: 10.1007/BF01008015. Virchows Arch. 1997. PMID: 9037314
-
Ewing's sarcoma precursors are highly enriched in embryonic osteochondrogenic progenitors.J Clin Invest. 2014 Jul;124(7):3061-74. doi: 10.1172/JCI72399. Epub 2014 Jun 9. J Clin Invest. 2014. PMID: 24911143 Free PMC article.
Cited by
-
LGR5 is Expressed by Ewing Sarcoma and Potentiates Wnt/β-Catenin Signaling.Front Oncol. 2013 Apr 15;3:81. doi: 10.3389/fonc.2013.00081. eCollection 2013. Front Oncol. 2013. PMID: 23596566 Free PMC article.
-
Ewing tumors that do not overexpress BMI-1 are a distinct molecular subclass with variant biology: a report from the Children's Oncology Group.Clin Cancer Res. 2011 Jan 1;17(1):56-66. doi: 10.1158/1078-0432.CCR-10-1417. Epub 2010 Nov 3. Clin Cancer Res. 2011. PMID: 21047978 Free PMC article.
-
3D tissue-engineered model of Ewing's sarcoma.Adv Drug Deliv Rev. 2014 Dec 15;79-80:155-71. doi: 10.1016/j.addr.2014.07.012. Epub 2014 Aug 7. Adv Drug Deliv Rev. 2014. PMID: 25109853 Free PMC article. Review.
-
The adolescent and young adult with cancer: state of the art -- bone tumors.Curr Oncol Rep. 2013 Aug;15(4):296-307. doi: 10.1007/s11912-013-0321-9. Curr Oncol Rep. 2013. PMID: 23690089 Review.
-
BMI-1 suppresses contact inhibition and stabilizes YAP in Ewing sarcoma.Oncogene. 2011 Apr 28;30(17):2077-85. doi: 10.1038/onc.2010.571. Epub 2010 Dec 20. Oncogene. 2011. PMID: 21170084 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources