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. 2007 Jun 7;1(1):15-16.
doi: 10.1016/j.stem.2007.05.016.

Stem cell epigenetics: is it all downhill from here?

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Stem cell epigenetics: is it all downhill from here?

Ron McKay. Cell Stem Cell. .
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Abstract

In this issue of Cell Stem Cell, Fasano et al. (2007) investigate the role of Bmi-1 in neural stem cells in vitro and in vivo. They find a progressively increasing requirement for Bmi-1 function in stem cells during development that, surprisingly, seems to involve regulation of the cell-cycle inhibitor p21.

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