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doi: 10.1016/j.stem.2007.05.016.
Stem cell epigenetics: is it all downhill from here?
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- PMID: 18371328
- DOI: 10.1016/j.stem.2007.05.016
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Stem cell epigenetics: is it all downhill from here?
Cell Stem Cell.
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Abstract
In this issue of Cell Stem Cell, Fasano et al. (2007) investigate the role of Bmi-1 in neural stem cells in vitro and in vivo. They find a progressively increasing requirement for Bmi-1 function in stem cells during development that, surprisingly, seems to involve regulation of the cell-cycle inhibitor p21.
Comment on
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shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development.Cell Stem Cell. 2007 Jun 7;1(1):87-99. doi: 10.1016/j.stem.2007.04.001. Cell Stem Cell. 2007. Retraction in: Cell Stem Cell. 2023 Jun 1;30(6):904. doi: 10.1016/j.stem.2023.05.009. PMID: 18371338 Retracted.
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