Stem cells remember their grade
- PMID: 18371344
- DOI: 10.1016/j.stem.2007.07.011
Stem cells remember their grade
Abstract
The stem cell state is understood based on what cells do in performance assays, crude measures of a highly refined state. In this issue of Cell Stem Cell, Dykstra et al. (2007) reveal stem cell gradation and the extent to which that gradation is retained in stem cell daughters of hematopoietic stem cells.
Comment on
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Long-term propagation of distinct hematopoietic differentiation programs in vivo.Cell Stem Cell. 2007 Aug 16;1(2):218-29. doi: 10.1016/j.stem.2007.05.015. Cell Stem Cell. 2007. PMID: 18371352