Human ES cell profiling broadens the reach of bivalent domains
- PMID: 18371354
- DOI: 10.1016/j.stem.2007.08.015
Human ES cell profiling broadens the reach of bivalent domains
Abstract
In this issue of Cell Stem Cell, Pan et al. (2007) and Zhao et al. (2007) report genome-wide histone H3 trimethylations at lysines 4 and 27 in human embryonic stem (ES) cells. Similar gene sets arise via different experimental systems, advancing our understanding of stem cell epigenetics.
Comment on
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Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells.Cell Stem Cell. 2007 Sep 13;1(3):286-98. doi: 10.1016/j.stem.2007.08.004. Cell Stem Cell. 2007. PMID: 18371363
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Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells.Cell Stem Cell. 2007 Sep 13;1(3):299-312. doi: 10.1016/j.stem.2007.08.003. Cell Stem Cell. 2007. PMID: 18371364
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