Stem cell regulation and host defense: the logic and the paradox
- PMID: 18371410
- DOI: 10.1016/j.stem.2007.12.002
Stem cell regulation and host defense: the logic and the paradox
Abstract
As a response against serious infection, there is often a need to produce more leukocytes to defend the organism against the infectious agent. In this issue of Cell Stem Cell, Goodell and colleagues (Feng et al., 2008) find a link between regulators of host defense and hematopoietic stem cells.
Comment on
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The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation.Cell Stem Cell. 2008 Jan 10;2(1):83-9. doi: 10.1016/j.stem.2007.10.007. Cell Stem Cell. 2008. PMID: 18371424 Free PMC article.
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