Wnt not, waste not
- PMID: 18371413
- DOI: 10.1016/j.stem.2007.12.005
Wnt not, waste not
Abstract
The molecular signals that regulate the regenerative function of satellite cells in the skeletal muscle remain largely obscure. In this issue of Cell Stem Cell, Brack et al. (2008) report that direct molecular crosstalk between stem cell self-renewal and differentiation pathways determines the timing and efficiency of muscle repair.
Comment on
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A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis.Cell Stem Cell. 2008 Jan 10;2(1):50-9. doi: 10.1016/j.stem.2007.10.006. Cell Stem Cell. 2008. PMID: 18371421
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