Why myc? An unexpected ingredient in the stem cell cocktail
- PMID: 18371417
- DOI: 10.1016/j.stem.2007.12.004
Why myc? An unexpected ingredient in the stem cell cocktail
Abstract
Screening cocktails of candidate genes for induction of pluripotency and self-renewal in nonstem cells has identified a surprising new embryonic stem cell regulator, the myc proto-oncogene. Here the possible mechanisms by which myc controls self-renewal and pluripotency are discussed.
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