Review
doi: 10.1016/j.stem.2008.01.007.
How do mesenchymal stromal cells suppress T cells?
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- PMID: 18371428
- DOI: 10.1016/j.stem.2008.01.007
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Review
How do mesenchymal stromal cells suppress T cells?
Cell Stem Cell.
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Abstract
Accumulating information indicates that mesenchymal stem or stromal cells (MSCs) are immunomodulatory, but the data to explain the observations are frequently conflicting. In this issue of Cell Stem Cell, Ren et al. (2008) provide evidence for a possible underlying mechanism of MSC-mediated T cell suppression. A perspective for considering these interesting observations is discussed.
Comment on
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Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide.Cell Stem Cell. 2008 Feb 7;2(2):141-50. doi: 10.1016/j.stem.2007.11.014. Cell Stem Cell. 2008. PMID: 18371435
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