Breast cancer surface receptors predict risk for developing brain metastasis and subsequent prognosis
- PMID: 18373884
- PMCID: PMC2397517
- DOI: 10.1186/bcr1868
Breast cancer surface receptors predict risk for developing brain metastasis and subsequent prognosis
Abstract
Determining the status of breast cancer surface receptors (estrogen receptor, progesterone receptor, HER2/neu) has become routine in the care of patients with this disease and has proven to be helpful in guiding treatment. For this reason, breast cancer has become a model for molecularly guided therapy in solid tumors. Emerging data support that these receptors are associated with risk for developing brain metastases. Additionally, once brain metastases have occurred these receptors may also correlate with prognosis.
Comment on
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Breast cancer subtypes and survival in patients with brain metastases.Breast Cancer Res. 2008;10(1):R20. doi: 10.1186/bcr1870. Epub 2008 Feb 28. Breast Cancer Res. 2008. PMID: 18307763 Free PMC article.
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