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. 2008 Aug;67(2):124-32.
doi: 10.1016/j.critrevonc.2008.01.013. Epub 2008 Mar 28.

The changing prevalence of comorbidity across the age spectrum

Jay F Piccirillo  1 , Anna Vlahiotis, Laurel B Barrett, Kellie L Flood, Edward L Spitznagel, Ewout W Steyerberg
Affiliations

The changing prevalence of comorbidity across the age spectrum

Jay F Piccirillo et al. Crit Rev Oncol Hematol. 2008 Aug.

Abstract

The purpose of the research was to demonstrate that comorbid health conditions disproportionately affect elderly cancer patients. Descriptive analyses and stacked area charts were used to examine the prevalence and severity of comorbid ailments by age of 27,506 newly diagnosed patients treated at one of eight cancer centers between 1998 and 2003. Hypertension was the most common ailment in all patients, diabetes was the second most prevalent ailment in middle-aged patients, and previous solid tumor(s) were the second most prevalent ailment in patients aged 74 and older. Although the prevalence and severity of comorbid ailments including dementia and congestive heart failure increased with age, some comorbidities such as HIV/AIDS and obesity decreased. Advances in cancer interventions have increased survivorship, but the impact of the changing prevalence and severity of comorbidities at different ages has implications for targeted research into targeted clinical and psychosocial interventions.

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Conflict of interest statement

Conflict of Interest Statement: None of the authors have any conflicts of interest. This research was supported by a grant from the National Cancer Institute (R01 CA10479-01). Study sponsors had no involvement in study design, in the collection, analysis and interpretation of data, in the writing of the manuscript, or in the decision to submit the manuscript for publication.

Figures

Figure 1
Figure 1
Prevalence of overall comorbidity by severity across the age spectrum
Figure 2(2.A - 2.F)
Figure 2(2.A - 2.F)
Prevalence of various comorbid ailments by severity across the age spectrum.

  1. 2.A Dementia

  2. 2.B. Congestive Heart Failure

  3. 2.C Previous Solid Tumor(s)

  4. 2.D HIV/AIDS

  5. 2.E Diabetes Mellitus

  6. 2.F Hypertension

Figure 2(2.A - 2.F)
Figure 2(2.A - 2.F)
Prevalence of various comorbid ailments by severity across the age spectrum.

  1. 2.A Dementia

  2. 2.B. Congestive Heart Failure

  3. 2.C Previous Solid Tumor(s)

  4. 2.D HIV/AIDS

  5. 2.E Diabetes Mellitus

  6. 2.F Hypertension

Figure 2(2.A - 2.F)
Figure 2(2.A - 2.F)
Prevalence of various comorbid ailments by severity across the age spectrum.

  1. 2.A Dementia

  2. 2.B. Congestive Heart Failure

  3. 2.C Previous Solid Tumor(s)

  4. 2.D HIV/AIDS

  5. 2.E Diabetes Mellitus

  6. 2.F Hypertension

Figure 2(2.A - 2.F)
Figure 2(2.A - 2.F)
Prevalence of various comorbid ailments by severity across the age spectrum.

  1. 2.A Dementia

  2. 2.B. Congestive Heart Failure

  3. 2.C Previous Solid Tumor(s)

  4. 2.D HIV/AIDS

  5. 2.E Diabetes Mellitus

  6. 2.F Hypertension

Figure 2(2.A - 2.F)
Figure 2(2.A - 2.F)
Prevalence of various comorbid ailments by severity across the age spectrum.

  1. 2.A Dementia

  2. 2.B. Congestive Heart Failure

  3. 2.C Previous Solid Tumor(s)

  4. 2.D HIV/AIDS

  5. 2.E Diabetes Mellitus

  6. 2.F Hypertension

Figure 2(2.A - 2.F)
Figure 2(2.A - 2.F)
Prevalence of various comorbid ailments by severity across the age spectrum.

  1. 2.A Dementia

  2. 2.B. Congestive Heart Failure

  3. 2.C Previous Solid Tumor(s)

  4. 2.D HIV/AIDS

  5. 2.E Diabetes Mellitus

  6. 2.F Hypertension

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References

    1. Yancik R, Ries LA. Cancer in older persons: an international issue in an aging world. Semin Oncol. 2004;31(2):128–136. - PubMed
    1. Balducci L. Epidemiology of cancer and aging. J Oncol Manag. 2005;14(2):47–50. - PubMed
    1. Yancik R, Ries LA. Aging and cancer in America. Demographic and epidemiologic perspectives. Hemato Oncol Clin North Am. 2000;14(1):17–23. - PubMed
    1. Balducci L, Extermann M. Cancer and aging. An evolving panorama. Hematol Oncol Clin North Am. 2000;14(1):1–16. - PubMed
    1. Edwards BK, Howe HL, Ries LA, et al. Annual report to the nation on the status of cancer, 1973-1999, featuring implications of age and aging on U.S. cancer burden. Cancer. 2002;94(10):2766–2792. - PubMed

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