Sex disparities in the treatment and control of cardiovascular risk factors in type 2 diabetes
- PMID: 18375411
- PMCID: PMC2453666
- DOI: 10.2337/dc08-0194
Sex disparities in the treatment and control of cardiovascular risk factors in type 2 diabetes
Abstract
Objective: To assess whether sex differences exist in the effective control and medication treatment intensity of cardiovascular disease (CVD) risk factors.
Research design and methods: We performed a cross-sectional analysis including 44,893 patients with type 2 diabetes (51% women). End points included uncontrolled CVD risk factors (LDL cholesterol > or =130 mg/dl, systolic blood pressure [SBP] > or =140 mmHg, and A1C > or =8%) and the intensity of medical management in patients with uncontrolled CVD risk factors. Multiple-adjusted odds ratios were calculated after stratification for the presence of CVD (present in 39% of the patients).
Results: Women with CVD were less likely to have SBP, LDL cholesterol, and A1C controlled and less likely to receive intensive lipid-lowering treatment. Women without CVD were less likely than men to have LDL cholesterol controlled with no differences in SBP or A1C control.
Conclusions: Women with diabetes and CVD have poorer control of important modifiable risk factors than men and receive less intensified lipid-lowering treatment.
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