Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2007 Mar-Apr;2(2):104-9.
doi: 10.1111/j.1747-0803.2007.00081.x.

Update on randomized clinical trials impacting clinical care in pediatric cardiac intensive care

Sarah Tabbutt  1 , Chitra Ravishankar
Affiliations
Review

Update on randomized clinical trials impacting clinical care in pediatric cardiac intensive care

Sarah Tabbutt et al. Congenit Heart Dis. 2007 Mar-Apr.

Abstract

Clinical trials addressing the management of infants and children with congenital heart disease are challenged by low numbers of patients with a similar diagnosis (inadequate power), variation in management strategies between institutions (difficulty developing multicentered protocols), a rapidly evolving field (equipoise), and insufficient funding. This article summarizes the challenges and the results of some single-center and multicenter trials evaluating perioperative care of infants and children undergoing surgery for congenital heart disease.

PubMed Disclaimer

MeSH terms