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. 2008 May;74(10):3315-8.
doi: 10.1128/AEM.02148-07. Epub 2008 Mar 31.

Use of murine norovirus as a surrogate to evaluate resistance of human norovirus to disinfectants

Gaël Belliot  1 , Amandine Lavaux, Donya Souihel, Davide Agnello, Pierre Pothier
Affiliations

Use of murine norovirus as a surrogate to evaluate resistance of human norovirus to disinfectants

Gaël Belliot et al. Appl Environ Microbiol. 2008 May.

Abstract

Murine norovirus (MNV) was used as a surrogate to study resistance of human norovirus to disinfectants used in hospitals. MNV was sensitive to alcohol, alcohol hand rubs, bleach, and povidone iodine-based disinfectant. Real-time reverse transcription-PCR results indicated that the presence of viral RNA did not correlate with the presence of infectious virus.

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References

    1. Baert, L., C. E. Wobus, E. Van Coillie, L. B. Thackray, J. Debevere, and M. Uyttendaele. 2008. Detection of murine norovirus 1 by using plaque assay, transfection assay, and real-time reverse transcription-PCR before and after heat exposure. Appl. Environ. Microbiol. 74:543-546. - PMC - PubMed
    1. Cannon, J. L., E. Papafragkou, G. W. Park, J. Osborne, L. A. Jaykus, and J. Vinje. 2006. Surrogates for the study of norovirus stability and inactivation in the environment: a comparison of murine norovirus and feline calicivirus. J. Food Prot. 69:2761-2765. - PubMed
    1. Cheesbrough, J. S., L. Barkess-Jones, and D. W. Brown. 1997. Possible prolonged environmental survival of small round structured viruses. J. Hosp. Infect. 35:325-326. - PubMed
    1. Chen, R., J. D. Neill, J. S. Noel, A. M. Hutson, R. I. Glass, M. K. Estes, and B. V. Prasad. 2004. Inter- and intragenus structural variations in caliciviruses and their functional implications. J. Virol. 78:6469-6479. - PMC - PubMed
    1. Dolin, R., N. R. Blacklow, H. DuPont, R. F. Buscho, R. G. Wyatt, J. A. Kasel, R. Hornick, and R. M. Chanock. 1972. Biological properties of Norwalk agent of acute infectious nonbacterial gastroenteritis. Proc. Soc. Exp. Biol. Med. 140:578-583. - PubMed

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