Connexin specificity of second messenger permeation: real numbers at last
- PMID: 18378797
- PMCID: PMC2279170
- DOI: 10.1085/jgp.200809998
Connexin specificity of second messenger permeation: real numbers at last
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Gap junction channels exhibit connexin-specific permeability to cyclic nucleotides.J Gen Physiol. 2008 Apr;131(4):293-305. doi: 10.1085/jgp.200709934. J Gen Physiol. 2008. PMID: 18378798 Free PMC article.
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References
-
- Ayad, W.A., D. Locke, I.V. Koreen, and A.L. Harris. 2006. Heteromeric, but not homomeric, connexin channels are selectively permeable to inositol phosphates. J. Biol. Chem. 281:16727–16739. - PubMed
-
- Bacskai, B.J., B. Hochner, M. Mahaut-Smith, S.R. Adams, B.K. Kaang, E.R. Kandel, and R.Y. Tsien. 1993. Spatially resolved dynamics of cAMP and protein kinase A subunits in Aplysia sensory neurons. Science. 260:222–226. - PubMed
-
- Bedner, P., H. Niessen, B. Odermatt, K. Willecke, and H. Harz. 2003. A method to determine the relative cAMP permeability of connexin channels. Exp. Cell Res. 291:25–35. - PubMed
-
- Bedner, P., H. Niessen, B. Odermatt, M. Kretz, K. Willecke, and H. Harz. 2006. Selective permeability of different connexin channels to the second messenger cyclic AMP. J. Biol. Chem. 281:6673–6681. - PubMed
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