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. 2008 Apr;56(4):607-9.
doi: 10.1248/cpb.56.607.

One-pot synthesis of simple alkaloids: 2,3-polymethylene-4(3H)-quinazolinones, luotonin A, tryptanthrin, and rutaecarpine

Katherine Chae Jahng  1 , Seung Ill Kim, Dong Hyeon Kim, Chang Seob Seo, Jong-Keun Son, Seung Ho Lee, Eung Seok Lee, Yurngdong Jahng
Affiliations

One-pot synthesis of simple alkaloids: 2,3-polymethylene-4(3H)-quinazolinones, luotonin A, tryptanthrin, and rutaecarpine

Katherine Chae Jahng et al. Chem Pharm Bull (Tokyo). 2008 Apr.

Abstract

One-pot synthesis of various 2,3-polymethylene-4(3H)-quinazolinones from anthranilic acid, corresponding lactam and SOCl(2) is described, which can be applicable to the synthesis of simple 4(3H)-quinazolinone-derived alkaloids, such as luotonin A, tryptanthrin, and rutaecarpine.

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