Comment
doi: 10.1038/ki.2008.69.
Connecting the interpodocyte slit diaphragm and actin dynamics: Emerging role for the nephrin signaling complex
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- PMID: 18379524
- DOI: 10.1038/ki.2008.69
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Comment
Connecting the interpodocyte slit diaphragm and actin dynamics: Emerging role for the nephrin signaling complex
Kidney Int.
2008 Apr.
Free article
Abstract
Uchida et al. show in this issue that in rat and human nephrosis, tyrosine phosphorylation of nephrin is reduced, and this is accompanied by a decrease in F-actin in glomeruli. This, together with previous studies, suggests that the nephrin protein complex is a signaling nexus that regulates actin dynamics in podocytes.
Comment on
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Decreased tyrosine phosphorylation of nephrin in rat and human nephrosis.Kidney Int. 2008 Apr;73(8):926-32. doi: 10.1038/ki.2008.19. Epub 2008 Feb 6. Kidney Int. 2008. PMID: 18256598
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