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Review
. 2008 Aug;22(2):99-105.
doi: 10.1007/s10840-008-9244-z. Epub 2008 Apr 1.

Cellular replacement therapy for arrhythmia treatment: early clinical experience

Demosthenes Katritsis  1
Affiliations
Review

Cellular replacement therapy for arrhythmia treatment: early clinical experience

Demosthenes Katritsis. J Interv Card Electrophysiol. 2008 Aug.

Abstract

Clinical and experimental studies have demonstrated the proarrhythmic potential of skeletal myoblast transplantation for repair of infarcted myocardium. The evidence on proarrhythmia following bone marrow-derived stem cells, and particular msenchymal stem cells, transplantation is inconclusive. There are experimental and preliminary clinical data supporting the possibility that mesenchymal stem cell transplantation might exert an anti-arrhythmic action by intervening with myocardial scar remodeling. However, clinical experience is limited.

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