Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 May;27(5):457-9.
doi: 10.1097/INF.0b013e3181646d6f.

HIV-1 drug resistance in HIV-1-infected children in the United Kingdom from 1998 to 2004

Rana Chakraborty  1 , Colette J Smith, David Dunn, Hannah Green, Trinh Duong, Katja Doerholt, Andrew Riordon, Hermione Lyall, Pat Tookey, Karina Butler, Caroline A Sabin, Di Gibb, Deenan Pillay; Collaborative HIV Paediatric Study; UK Collaborative Group on HIV Drug Resistance
Collaborators, Affiliations

HIV-1 drug resistance in HIV-1-infected children in the United Kingdom from 1998 to 2004

Rana Chakraborty et al. Pediatr Infect Dis J. 2008 May.

Abstract

We reviewed HIV-1 genotypes from 200 of 979 (20%) HIV-infected children in the U.K. Collaborative HIV in Pediatric Study (CHIPS) cohort (343 resistance tests). Three of 44 samples had major primary resistance mutations before antiretroviral therapy. Three-class resistance was noted in 42 samples (14.1%). Our study also highlighted underutilization of testing and the need for prompt genotyping after drug discontinuation which may have lead to an underestimation of HIV-1 resistance.

PubMed Disclaimer

LinkOut - more resources