Tracheobronchial amyloidosis: utilization of radiotherapy as a treatment modality

Abstract

Tracheobronchial amyloidosis (TBA) is a rare disease. No general consensus exists with regard to its optimal treatment, resulting in a variety of modalities used to manage this condition. In this article, we present a case of TBA treated with external beam radiation therapy with encouraging results. A brief literature review of this rare ailment is also included.

Figure 1

Biopsy indicating amyloid deposition in the bronchial wall lamina propria below the mucosal surface. (100× magnification)

Figure 2

Chest x-ray depicting (A) partial right upper lobe collapse, (B) with subsequent resolution after radiation therapy.

Figure 3

Bronchoscopic pictures depicting (A) mass at right upper lobe airway, (B) with subsequent improvement after radiation therapy.