Outcome assessment in patients with chronic obstructive rhinitis CO2 laser treated
- PMID: 18383755
- PMCID: PMC2639950
Outcome assessment in patients with chronic obstructive rhinitis CO2 laser treated
Abstract
Surgical lasers have been used to restore nasal flow in chronic obstructive rhinitis, with a significant improvement in symptoms having been reported in almost all cases. However, evidence supporting the efficacy at long-term, and studies on the assessment of quality of life remain limited. In the present study, efficacy at long term and improvement in the quality of life were assessed in patients with chronic obstructive rhinitis, treated with CO2 laser. A total of 308 patients with chronic obstructive rhinitis were enrolled. The primary outcome measure assessed was the change in score regarding specific and general symptoms, between baseline to 2-4.5 and 7.8 mean years follow-up. Laser turbinotomy restored nasal flow and induced a change in total score which was statistically significant, for specific and general symptoms at the first, second and third follow-up, p < 0.01. CO2 laser turbinate surgery improved symptoms and quality of life in patients with chronic obstructive rhinitis as observed at 2-4.5 and 7.8 mean years follow-up.
La chirurgia laser è stata impiegata nel ripristino della pervietà nasale nei soggetti affetti da rinite cronica ostruttiva (COR); la maggior parte degli Autori riporta un significativo miglioramento della sintomatologia. Sono tuttavia pochi gli studi che ne supportino l’efficacia a lungo termine e che valutino l’impatto sulla qualità di vita (QoL). Gli Autori hanno valutato i risultati a lungo termine e la QoL nei pazienti affetti da COR, trattati con il laser a CO2. Sono stati inclusi nello studio 308 pazienti con rinite cronica ostruttiva. Il principale parametro di valutazione di efficacia è stato il cambiamento in termini di score sintomatologico, per i sintomi generali e specifici, tra il tempo zero, il primo, secondo e terzo follow-up (tempo medio 2-4,5 e 7,8 anni). Lo studio evidenzia che la turbinotomia effettuata con il laser a CO2 ripristina il flusso respiratorio nasale ed induce modifiche statisticamente significative negli score totali per i sintomi generali e specifici al primo, secondo e terzo follow-up, migliorando la QoL.
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