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. 2006 Feb;26(1):32-7.

Outcome assessment in patients with chronic obstructive rhinitis CO2 laser treated

Affiliations

Outcome assessment in patients with chronic obstructive rhinitis CO2 laser treated

D Testa et al. Acta Otorhinolaryngol Ital. 2006 Feb.

Abstract

Surgical lasers have been used to restore nasal flow in chronic obstructive rhinitis, with a significant improvement in symptoms having been reported in almost all cases. However, evidence supporting the efficacy at long-term, and studies on the assessment of quality of life remain limited. In the present study, efficacy at long term and improvement in the quality of life were assessed in patients with chronic obstructive rhinitis, treated with CO2 laser. A total of 308 patients with chronic obstructive rhinitis were enrolled. The primary outcome measure assessed was the change in score regarding specific and general symptoms, between baseline to 2-4.5 and 7.8 mean years follow-up. Laser turbinotomy restored nasal flow and induced a change in total score which was statistically significant, for specific and general symptoms at the first, second and third follow-up, p < 0.01. CO2 laser turbinate surgery improved symptoms and quality of life in patients with chronic obstructive rhinitis as observed at 2-4.5 and 7.8 mean years follow-up.

La chirurgia laser è stata impiegata nel ripristino della pervietà nasale nei soggetti affetti da rinite cronica ostruttiva (COR); la maggior parte degli Autori riporta un significativo miglioramento della sintomatologia. Sono tuttavia pochi gli studi che ne supportino l’efficacia a lungo termine e che valutino l’impatto sulla qualità di vita (QoL). Gli Autori hanno valutato i risultati a lungo termine e la QoL nei pazienti affetti da COR, trattati con il laser a CO2. Sono stati inclusi nello studio 308 pazienti con rinite cronica ostruttiva. Il principale parametro di valutazione di efficacia è stato il cambiamento in termini di score sintomatologico, per i sintomi generali e specifici, tra il tempo zero, il primo, secondo e terzo follow-up (tempo medio 2-4,5 e 7,8 anni). Lo studio evidenzia che la turbinotomia effettuata con il laser a CO2 ripristina il flusso respiratorio nasale ed induce modifiche statisticamente significative negli score totali per i sintomi generali e specifici al primo, secondo e terzo follow-up, migliorando la QoL.

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Figures

Fig. 1
Fig. 1
Custom self-retaining nasal speculum allows surgeon to have both hands free, making laser treatment easier to perform and in less time.
Fig. 2
Fig. 2
CO2 laser cuts tissue and makes a groove along superomedial border of inferior turbinate from anterior to posterior end along entire length.
Fig. 3
Fig. 3
Decrease in total airway resistance in patients with chronic obstructive rhinitis following CO2 laser treatment, at first, second and third follow-up.
Fig. 4
Fig. 4
Mean specific (o) and general (■) symptom scores recorded in 140 hypertrophic rhinitis patients before, at mean 2, 4.5 and 7.8 years after laser turbinotomy.
Fig. 5
Fig. 5
Fig. 5. Mean specific (o) and general (■) symptom scores recorded in 168 allergic rhinitis patients before, at mean 2, 4.5 and 7.8 years after laser turbinotomy.
Fig. 6
Fig. 6
Overall quality of life evaluation expressed as mean of specific and general symtoms for a total of 8 items for hypertrophic rhinitis (*) and 11 items for allergic rhinitis (•) patients, before, at mean 2, 4.5 and 7.8 years after CO2 laser turbinotomy.

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