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. 2008 Apr 23;130(16):5416-7.
doi: 10.1021/ja800164z. Epub 2008 Apr 2.

Disassembly of noncovalent amphiphilic polymers with proteins and utility in pattern sensing

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Disassembly of noncovalent amphiphilic polymers with proteins and utility in pattern sensing

Elamprakash N Savariar et al. J Am Chem Soc. .

Abstract

A simple strategy for pattern recognition of proteins through micellar disassembly is introduced. Five different noncovalently assembled receptors have been generated, and the disassembly was studied by monitoring the encapsulated dye release in response to five different proteins. The disassembly induced fluorescence change of the guest molecule produces protein-specific patterns.

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