Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Apr 1;5(4):e81.
doi: 10.1371/journal.pmed.0050081.

Improving defences at the portal of HIV entry: mucosal and innate immunity

Robin J Shattock  1 , Barton F Haynes, Bali Pulendran, Jorge Flores, José Esparza; Working Group convened by the Global HIV Vaccine Enterprise
Collaborators, Affiliations

Improving defences at the portal of HIV entry: mucosal and innate immunity

Robin J Shattock et al. PLoS Med. .

Abstract

The authors discuss the key scientific issues in mucosal and innate immunity related to immune protection against HIV infection.

PubMed Disclaimer

Conflict of interest statement

Competing Interests: BFH is Principal Investigator of the National Institutes of Health–funded Center for HIV-AIDS Vaccine Immunology; his Duke Human Vaccine Institute has a National Institutes of Health contract in partnership with Wyeth to develop therapeutic HIV vaccines. The remaining authors declare that they have no competing interests.

References

    1. Coordinating Committee of the Global HIV/AIDS Vaccine Enterprise. The Global HIV/AIDS Vaccine Enterprise: Scientific strategic plan. PLoS Med. 2005;2:e25. doi: . - DOI - PMC - PubMed
    1. Pope M, Haase AT. Transmission, acute HIV-1 infection and the quest for strategies to prevent infection. Nat Med. 2003;9:847–852. - PubMed
    1. Lackner AA, Veazey RS. Current concepts in AIDS pathogesis: insights from the SIV/macaque model. Annu Rev Med. 2007;58:461–476. - PubMed
    1. Zhang L, He T, Talal A, Wang G, Frankel SS, et al. In vivo distribution of the human immunodeficiency virus/simian immunodeficiency virus coreceptors: CXCR4, CCR3, and CCR5. J Virol. 1998;72:5035–5045. - PMC - PubMed
    1. Patterson BK, Landay A, Andersson J, Brown C, Behbahani H, et al. Repertoire of chemokine receptor expression in the female genital tract: implications for human immunodeficiency virus transmission. Am J Pathol. 1998;153:481–490. - PMC - PubMed