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Review
. 2008 Jun;53(1):1-7.
doi: 10.1111/j.1574-695X.2008.00378.x. Epub 2008 Apr 1.

Toll-like receptors and fungal infections: the role of TLR2, TLR4 and MyD88 in paracoccidioidomycosis

Vera L G Calich  1 , Adriana Pina, Maíra Felonato, Simone Bernardino, Tania A Costa, Flávio V Loures
Affiliations
Free article
Review

Toll-like receptors and fungal infections: the role of TLR2, TLR4 and MyD88 in paracoccidioidomycosis

Vera L G Calich et al. FEMS Immunol Med Microbiol. 2008 Jun.
Free article

Abstract

The aim of this minireview is to present a concise view of the most important pattern recognition receptors used by the innate immune system to sense and control pathogen growth into host tissues. A brief review of the role of Toll-like receptors (TLRs) in fungal infections followed by some recent results on the function of TLR4, TLR2 and the MyD88 adaptor molecule in the pathogenesis of paracoccidioidomycosis are presented.

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