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Comparative Study
. 2008:2008:631414.
doi: 10.1155/2008/631414.

Comparison of C-reactive protein and serum amyloid a protein in septic shock patients

Domingos Dias Cicarelli  1 , Joaquim Edson Vieira, Fábio Ely Martins Benseñor
Affiliations
Comparative Study

Comparison of C-reactive protein and serum amyloid a protein in septic shock patients

Domingos Dias Cicarelli et al. Mediators Inflamm. 2008.

Abstract

Septic shock is a severe inflammatory state caused by an infectious agent. Our purpose was to investigate serum amyloid A (SAA) protein and C-reactive protein (CRP) as inflammatory markers of septic shock patients. Here we evaluate 29 patients in postoperative period, with septic shock, in a prospective study developed in a surgical intensive care unit. All eligible patients were monitored over a 7-day period by sequential organ failure assessment (SOFA) score, daily CRP, SAA, and lactate measurements. CRP and SAA strongly correlated up to the fifth day of observation but were not good predictors of mortality in septic shock.

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Figures

Figure 1
Figure 1
CRP evolution of survivors and nonsurvivors during the first week (NS). NS: not statistically significant.
Figure 2
Figure 2
SAA evolution of survivors and nonsurvivors during the first week (NS). NS: not statistically significant.
See this image and copyright information in PMC

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