[Immunization of the nude mouse against mouse hepatitis virus through the transfer of sensitized lymphocytes]
[Article in
French]
- PMID: 183876
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[Immunization of the nude mouse against mouse hepatitis virus through the transfer of sensitized lymphocytes]
[Article in
French]
C R Seances Soc Biol Fil.
1976.
Abstract
Nude (nu/nu) mice failed to resist to virulent mouse hepatitis virus (MHV) infection after vaccination with inactivated virus. Resistance was induced in nu/nu mice by the transfer of spleen cells from heterozygous haired (nu/ +) mice concomitantly with the vaccination, and the effect was more remarkable with spleen cells from immunized nu/ + mice. Antibody was demonstrable in nu/nu mice having received nu/ + cells and survived challenge infection.
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