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. 2008 Mar-Apr;4(2):158-61.
doi: 10.4161/hv.4.2.4871. Epub 2007 Aug 14.

Meningococcal B vaccine development and evaluation of efficacy

Loek van Alphen  1 , Germie van den Dobbelsteen
Affiliations

Meningococcal B vaccine development and evaluation of efficacy

Loek van Alphen et al. Hum Vaccin. 2008 Mar-Apr.

Abstract

In this commentary we stress that serum bactericidal activity is now internationally accepted as correlate of protection for evaluating new vaccines for epidemic and endemic meningococcal B control, and that the standardization of the assay and the choice of representative strains for each of the vaccine candidates are critical.

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