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Review
. 2007 Oct-Dec;111(4):1001-4.

[MLPA technique--principles and use in practice]

[Article in Romanian]
Cristina Rusu  1 , Adriana Sireteanu, Maria Puiu, Cristina Skrypnyk, E Tomescu, Katalin Csep, Victoria Creţ, Ligia Barbarii
Affiliations
  • PMID: 18389795
Review

[MLPA technique--principles and use in practice]

[Article in Romanian]
Cristina Rusu et al. Rev Med Chir Soc Med Nat Iasi. 2007 Oct-Dec.

Abstract

MLPA (Multiplex Ligation-dependent Probe Amplification) is a recently introduced method, based on PCR principle, useful for the detection of different genetic abnormalities (aneuploidies, gene deletions/duplications, subtelomeric rearrangements, methylation status etc). The technique is simple, reliable and cheap. We present this method to discuss its importance for a modern genetic service and to underline its multiple advantages.

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